Methods for Assessing Mitochondrial Function in Diabetes
نویسندگان
چکیده
منابع مشابه
Methods for Assessing Mitochondrial Function in Diabetes
A growing body of research is investigating the potential contribution of mitochondrial function to the etiology of type 2 diabetes. Numerous in vitro, in situ, and in vivo methodologies are available to examine various aspects of mitochondrial function, each requiring an understanding of their principles, advantages, and limitations. This review provides investigators with a critical overview ...
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15 صفحه اولAssessing Multiple Features of Mitochondrial Function
A lterations of energy metabolism are key features of insulin resistance, diabetes, and diabetesrelated complications. However, the role of mitochondria—the cell’s power plants—in abnormal metabolism is less certain. Mitochondria are responsible for oxidative phosphorylation, which couples substrate oxidation to synthesize ATP. Essentially, the reduction of dinucleotides enables electrons to tr...
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ژورنال
عنوان ژورنال: Diabetes
سال: 2013
ISSN: 0012-1797,1939-327X
DOI: 10.2337/db12-1219